The Holy Hangover Cure (© Unseen University) is a mixture that the UU wizards cooked up to cure the Oh-God of Hangovers in Terry Pratchett's Hogfather. The Holy Hangover Cure is composed of (among other things): raw eggs, fresh orange juice, Klatchian coffee, mustard, horseradish, cream, anchovies, willow bark, yogurt, Englebert's Enhancer, and a pint bottle of wow-wow sauce. As this would clearly kill any non-godly creatures, and cause godly ones severe-to-nuclear-war-level indigestion, it is firmly recommended that nobody drink this. Ever. At all. Not even to see what happens.
Diocletian uses a tamer version of the HHC in her concoction of Blumble,[1] "in order to distract and dilute the essential aura of Nanny Oggish alcoholic nastiness."[2] The cream is left out, as is Englebert's Enhancer. The wow-wow sauce is available to anybody willing to risk it, but only a couple of drops were in the stuff that Dio gave the SO.[1]
Putting it up against a Pan Galactic Gargleblaster or Pan Galactic Gargle Bleeprin Blaster is likely not advised.